2024
Highly efficient in vivo C-to-T base editing in Atlantic salmon (Salmo salar) – A step towards aquaculture precision breeding
Mari Torsdotter Raudstein, Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Morten Barvik, Ståle Ellingsen, Rolf Brudvik Edvardsen
Aquaculture
581
2023
In vivo CRISPR/LbCas12a-mediated knock-in and knock-out in Atlantic salmon (Salmo salar L.)
Mari Torsdotter Raudstein, Erik Nordtorp Kjærner-Semb, Morten Barvik, Silje Broll, Anne Hege Straume, Rolf Brudvik Edvardsen
Transgenic research
2021
Single nucleotide replacement in the Atlantic salmon genome using CRISPR/Cas9 and asymmetrical oligonucleotide donors
Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Hilal Guralp, Simon Lillico, Anna Wargelius, Rolf Brudvik Edvardsen
BMC Genomics
22
2020
Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon
Hilal Guralp, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Anne Hege Straume, Lene Kleppe, Rüdiger W. Schulz, Rolf Brudvik Edvardsen, Anna Wargelius
Scientific Reports
10
2020
The novel microRNAs hsa-miR-nov7 and hsamiR- nov3 are over-expressed in locally advanced breast cancer
Deepak Poduval, Zuzana Sichmanovà, Anne Hege Straume, Per Eystein Lønning, Stian Knappskog
PLOS ONE
15:e0225357
p. 1-23
2020
Indel locations are determined by template polarity in highly efficient in vivo CRISPR/Cas9- mediated HDR in Atlantic salmon
Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Hilal Guralp, Lene Kleppe, Anna Wargelius, Rolf Brudvik Edvardsen
Scientific Reports
10
2019
MYC-induced miR-203b-3p and miR-203a-3p control Bcl-xL expression and paclitaxel sensitivity in tumor cells
Sofia Aakko, Anne Hege Straume, Einar Elvbakken Birkeland, Ping Chen, Xi Qiao, Per Eystein Lønning, Marko J. Kallio
Translational Oncology
12
p. 170-179
2019
MYC-Induced miR-203b-3p and miR-203a-3p Control Bcl-xL Expression and Paclitaxel Sensitivity in Tumor Cells.
Aakko S, Straume AH, Birkeland EE, Chen P, Qiao X, Lønning PE, Kallio MJ.
Transl Oncol.
12(1)
p. 170-179
2016
Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells' sensitivity to paclitaxel
Mahesh Balasaheb Tambe, Sofia Pruikkonen, Jenni Heidi Eveliina Mäki-Jouppila, Ping Chen, Bente Vilming Elgaaen, Anne Hege Straume, Kaisa Huhtinen, Olli Carpén, Per Eystein Lønning, Ben Davidson, Sampsa Hautaniemi, Marko Johannes Kallio
OncoTarget
7
p. 12267-12285
2016
Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells' sensitivity to
Tambe M, Pruikkonen S, Mäki-Jouppila J,Chen P, Vilming Elgaaen B, Straume AH, Huhtinen K, Cárpen O, Lønning PE, Davidson B, Hautaniemi S, Kallio MJ
Oncotarget
2014
Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissue
Anne Hege Straume, Stian Knappskog, Per Eystein Lønning
Journal of Steroid Biochemistry and Molecular Biology
143
p. 192-198
2014
Effects of SNP variants in the 17β-HSD2 and 17β-HSD7 genes and 17β-HSD7 copy number on gene transcript and estradiol levels in breast cancer tissue
Anne Hege Straume, Stian Knappskog, Per Eystein Lønning
J Steroid Biochem Molec Biol;
18:143C
p. 192-198
2012
Effect of CYP19 rs6493497 and rs7176005 haplotype status on in vivo aromatase transcription, plasma and tissue estrogen levels in postmenopausal women
Anne Hege Straume, Stian Knappskog, Per Eystein Lønning
Journal of Steroid Biochemistry and Molecular Biology
128
p. 69-75
2012
Elevated levels of the steroidogenic factor 1 are associated with over-expression of CYP19 in an oestrogen-producing testicular Leydig cell tumour
Anne Hege Straume, Kristian Løvås, Hrvoje Miletic, Karsten Gravdal, Per Eystein Lønning, Stian Knappskog
European Journal of Endocrinology (EJE)
166
p. 941-949
2012
Elevated levels of the Steroidogenic Factor-1 are associated with over-expression of CYP19 in an Oestrogen producing testicular Leydig cell tumour
European Journal of Endocrinology
166
p. 941-949
2012
Effect of CYP19 rs6493497 and rs7176005 haplotype status on in vivo aromatase transcription, plasma and tissue estrogen levels in postmenopausal women
Straume AH, Knappskog S, Lønning PE
J Steroid Biochem Molec Biol;
128(1-2)
p. 69-75
2011
Exploring breast cancer estrogen disposition: The basis for endocrine manipulation
Per Eystein Lønning, Ben P. Haynes, Anne Hege Straume, Anita Dunbier, Hildegunn Helle, Stian Knappskog, Mitch Dowsett
Clinical Cancer Research
17
p. 4948-4958
2011
Recent data on intratumor estrogens in breast cancer
Per Eystein Lønning, Ben P. Haynes, Anne Hege Straume, Anita Dunbier, Hildegunn Helle, Stian Knappskog, Mitch Dowsett
Steroids
76
p. 786-791
2011
Recent data on intratumor estrogens in breast cancer
Steroids
76
p. 786-791
2011
Exploring breast cancer estrogen disposition: the basis for endocrine manipulation.
Clin Cancer Res
17
p. 4948-4958
2010
Intratumoral estrogen disposition in breast cancer
Ben P. Haynes, Anne Hege Straume, Jurgen Geisler, Roger A'Hern, Hildegunn Helle, Ian E Smith, Per Eystein Lønning, Mitch Dowsett
Clinical Cancer Research
16
p. 1790-1801
2010
Chk2 splice variants express a dominant-negative effect on the wild-type Chk2 kinase activity
Elisabet Ognedal Berge, Vidar Staalesen, Anne Hege Straume, Johan R. Lillehaug, Per Eystein Lønning
BBA - Molecular Cell Research
1803
p. 386-395
2010
Chk2 splice variants express a dominant-negative effect on the wild-type Chk2 kinase activity
Biochim Biophys Acta
1803
p. 386-396
2010
Intratumoral estrogen disposition in breast cancer
Clin Cancer Res
16
p. 1790-1801
2006
Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools
Frode Berven, Odd Andre Karlsen, Anne Hege Straume, Kristian Flikka, J. Collin Murrell, Anne Fjellbirkeland, Johan Lillehaug, Ingvar Eidhammer, Harald B Jensen
Archives of Microbiology
184
p. 362-377
2006
Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools
Arch Microbiol
184
p. 362-377
2024
Uses of biotechnology to control reproduction in Atlantic salmon
Lene Kleppe, Anna Sofie Troedsson Wargelius, Diego Crespo, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Eva Andersson, Per Gunnar Fjelldal, Tom Johnny Hansen, Rolf Brudvik Edvardsen, Anders Thorsen, Rüdiger W. Schulz, Anne Torsvik, Grethe Beate Thorsheim, Anne Hege Straume, Petra Vogelsang, Ivar Helge Matre, Ann-Kathrin Jakobsen Kroken, Lise Dyrhovden, Audun Østby Pedersen, Simon Flavell, Florian Sambraus, Arnor Gullanger, Tone Knappskog
2024
Moving sterile Crispr salmon from the tank to sea cages - regulatory barriers and social impacts
Anna Sofie Troedsson Wargelius, Erik Nordtorp Kjærner-Semb, Anne Hege Straume, Per Gunnar Fjelldal, Jonatan Nilsson, Hilal Guralp, Kai Ove Skaftnesmo, Dorothy Jane Dankel, Eva Andersson, Lene Kleppe, Rolf Brudvik Edvardsen
2019
Highly efficient CRISPR/Cas9 knock-in in Atlantic salmon
Rolf Brudvik Edvardsen, Anne Hege Straume, Erik Nordtorp Kjærner-Semb, hilal guralp, Lene Kleppe, Kai Ove Skaftnesmo, Anna Wargelius
2019
Highly efficient CRISPR/Cas9 knock-in in Atlantic Salmon
Anne Hege Straume, hilal guralp, Kai Ove Skaftnesmo, Anna Wargelius, Rolf Brudvik Edvardsen
2018
Optimization of CRISPR/Cas9 knock-in technology and application in salmon
Rolf Edvardsen, Anne Hege Straume, Kai Ove Skaftnesmo, Lene Kleppe, hilal guralp, Anna Wargelius