Rolf Brudvik Edvardsen

Researcher

E-mail: rolf.brudvik.edvardsen@hi.no

Telephone: 90942948

Department: Reproduksjon og utviklingsbiologi

Curriculum Vitae

My master of science (1996-1999) was carried out at the Department of Molecular Biology at the University of Bergen under the guidance of Prof. Anders Fjose. Here I studied the DNA binding properties of PAX proteins in zebrafish. The doctoral thesis (2000-2005) was conducted by Sars Int Centre for Marine Molecular Biology under the supervision of Prof. Daniel Chourrout. Here I studied various aspects of genes and genomes of the tunicate Oikopleura dioica.

From 2005 to 2010 I was Postdoctoral Fellow at IMR developing methodologies and resources in cod genomics. Since 2010 I have been a senior researcher in the research group Reproduction and Growth at IMR. From working mostly on cod the focus has shifted more over to salmon, but also halibut, haddock, calanus and salmon louse. The methodology is wide from bioinformatics studies (GWAS, epigentics, transcriptomics) to microinjections (CRISPR-cas9). The scientific questions are also differing much between the projects, but with an emphasis on using genomics to explore reproductive mechanisms in salmon

Publications

Academic articles

2024

Loss of bmp15 function in the seasonal spawner Atlantic salmon results in ovulatory failure

Diego Crespo, Per Gunnar Fjelldal, Tom Johnny Hansen, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Anders Thorsen, Birgitta Norberg, Rolf Brudvik Edvardsen, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius, Lene Kleppe

The FASEB Journal 38

2024

Highly efficient in vivo C-to-T base editing in Atlantic salmon (Salmo salar) – A step towards aquaculture precision breeding

Mari Torsdotter Raudstein, Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Morten Barvik, Ståle Ellingsen, Rolf Brudvik Edvardsen

Aquaculture 581

2024

Loss of Fshr Prevents Testicular Maturation in Atlantic Salmon (Salmo salar L.)

Eva Andersson, Rüdiger W. Schulz, Fernanda Almeida, Lene Kleppe, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Diego Crespo, Per Gunnar Fjelldal, Tom Johnny Hansen, Birgitta Norberg, Rolf Brudvik Edvardsen, Anna Wargelius

Endocrinology 165

2023

In vivo CRISPR/LbCas12a-mediated knock-in and knock-out in Atlantic salmon (Salmo salar L.)

Mari Torsdotter Raudstein, Erik Nordtorp Kjærner-Semb, Morten Barvik, Silje Broll, Anne Hege Straume, Rolf Brudvik Edvardsen

Transgenic research

2022

Heterochiasmy and the establishment of gsdf as a novel sex determining gene in Atlantic halibut

Rolf Brudvik Edvardsen, Ola Wallerman, Tomasz Furmanek, Lene Kleppe, Patric Jern, Andreas Wallberg, Erik Nordtorp Kjærner-Semb, Stig Mæhle, Sara Olausson, Elisabeth Sundström, Torstein Harboe, Ragnfrid Mangor-Jensen, Margareth Møgster Drønen, Prescilla Perrichon, Birgitta Norberg, Carl-Johan Rubin

PLoS Genetics 18

2022

Pituitary Gonadotropin Gene Expression During Induced Onset of Postsmolt Maturation in Male Atlantic Salmon: In Vivo and Tissue Culture Studies

Diego Crespo, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Ozlem Yilmaz, Birgitta Norberg, Sara Olausson, Petra Vogelsang, Jan Bogerd, Lene Kleppe, Rolf Brudvik Edvardsen, Eva Andersson, Anna Wargelius, Tom Johnny Hansen, Per Gunnar Fjelldal, Rüdiger W. Schulz

Frontiers in Endocrinology 13

2022

Impact of atioxidant feed and growth manipulation on the redox regulation of Atlantic salmon smolts

Peng Yin, Bjørn Thrandur Bjørnsson, Per Gunnar Fjelldal, Takaya Saito, Sofie C. Remø, Rolf Brudvik Edvardsen, Tom Johnny Hansen, Sandeep Sharma, Rolf Erik Olsen, Kristin Hamre

Antioxidants 11 p. 1-18

2022

Effect of diet on molecular relationships between Atlantic cod larval muscle growth dynamics, metabolism, and antioxidant defense system

Tu Anh Vo, Trina Falck Galloway, Augustine Arukwe, Rolf Brudvik Edvardsen, Kristin Hamre, Ørjan Karlsen, Ivar Rønnestad, Elin Kjørsvik

Frontiers in Marine Science 9 p. 1-19

2022

Full production cycle performance of gene-edited, sterile Atlantic salmon - growth, smoltification, welfare indicators and fillet composition

Lene Kleppe, Per Gunnar Fjelldal, Eva Andersson, Tom Johnny Hansen, Monica Sanden, Aina Bruvik, Kai Ove Skaftnesmo, Tomasz Furmanek, Erik Nordtorp Kjærner-Semb, Diego Crespo, Simon Flavell, Audun Østby Pedersen, Petra Vogelsang, Anja Torsvik, Karen Anita Kvestad, Sara Olausson, Birgitta Norberg, Rüdiger W. Schulz, J. Bogerd, N. Santi, Rolf Brudvik Edvardsen, Anna Wargelius

Aquaculture 560

2022

The Piwil1 N domain is required for germ cell survival in Atlantic salmon

Fernanda Loureiro Almeida, Kai Ove Skaftnesmo, Eva Andersson, Lene Kleppe, Rolf Brudvik Edvardsen, Birgitta Norberg, Per Gunnar Fjelldal, Tom Johnny Hansen, Rüdiger W. Schulz, Anna Wargelius

Frontiers in Cell and Developmental Biology 10

2022

Photoreception and transcriptomic response to light during early development of a teleost with a life cycle tightly controlled by seasonal changes in photoperiod

Mariann Eilertsen, David William Peter Dolan, Charlotte M. Bolton, Rita Karlsen, Wayne I.L. Davies, Rolf Brudvik Edvardsen, Tomasz Furmanek, Harald Sveier, Herve Migaud, Jon Vidar Helvik

PLoS Genetics 18

2021

Genome editing in food and feed production – implications for risk assessment. Scientific Opinion of the Scientific Steering Committee of the Norwegian Scientific Committee for Food and Environment

Johanna Eva Bodin, Tage Thorstensen, Muath K Alsheikh, Dean Basic, Rolf Brudvik Edvardsen, Knut Tomas Dalen, Nur Duale, Ole Martin Eklo, Åshild Gunilla Ergon, Anne-Marthe Ganes Jevnaker, Kjetil Hindar, Leiv Sigve Håvarstein, Martin Malmstrøm, Kaare Magne Nielsen, Siri Lie Olsen, Eli Knispel Rueness, Monica Sanden, Ville Erling Sipinen, Kristine von Krogh, Dag Inge Våge, Anna Wargelius, Per Hans Micael Wendell, Siamak Pour Yazdankhah, Jan Alexander, Ellen Merete Bruzell, Gro Ingunn Hemre, Vigdis Vandvik, Angelika Agdestein, Edel O. Elvevoll, Dag Olav Hessen, Merete Hofshagen, Trine Husøy, Helle Katrine Knutsen, Åshild Krogdahl, Asbjørn Magne Nilsen, Trond Rafoss, Olaug Taran Skjerdal, Inger-Lise Karin Steffensen, Tor Arne Strand, Gaute Velle, Yngvild Wasteson

VKM Report 2021

2021

Single nucleotide replacement in the Atlantic salmon genome using CRISPR/Cas9 and asymmetrical oligonucleotide donors

Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Hilal Guralp, Simon Lillico, Anna Wargelius, Rolf Brudvik Edvardsen

BMC Genomics 22

2021

Genome editing in food and feed production – implications for risk assessment. Opinion of the Steering Committee of the Norwegian Scientific Committee for Food and Environment

Johanna Eva Bodin, Tage Thorstensen, Muath Alsheikh, Dean Basic, Rolf Brudvik Edvardsen, Knut Tomas Dalen, Carlos Gonçalo das Neves, Nur Duale, Ole Martin Eklo, Åshild Gunilla Ergon, Anne-Marthe Ganes Jevnaker, Kjetil Hindar, Sigve Håvarstein, Martin Malmstrøm, Kaare Magne Nielsen, Siri Lie Olsen, Eli Knispel Rueness, Monica Sanden, Ville Erling Sipinen, Rose Vikse, Kristine von Krogh, Dag Inge Våge, Anna Sofie Troedsson Wargelius, Per Hans Micael Wendell, Siamak Pour Yazdankhah, Jan Alexander, Ellen Merete Bruzell, Gro Ingunn Hemre, Vigdis Vandvik, Angelika Agdestein, Edel O. Elvevoll, Dag Olav Hessen, Merete Hofshagen, Trine Husøy, Helle Katrine Knutsen, Åshild Krogdahl, Asbjørn Magne Nilsen, Trond Rafoss, Olaug Taran Skjerdal, Inger-Lise Karin Steffensen, Tor Arne Strand, Gaute Velle, Yngvild Wasteson

VKM Report 2021:18 p. 1-291

2021

Loss of stra8 Increases Germ Cell Apoptosis but Is Still Compatible With Sperm Production in Atlantic Salmon (Salmo salar)

Kai Ove Skaftnesmo, Diego Crespo, Lene Kleppe, Eva Andersson, Rolf Brudvik Edvardsen, Birgitta Norberg, Per Gunnar Fjelldal, Tom Johnny Hansen, Rüdiger W. Schulz, Anna Wargelius

Frontiers in Cell and Developmental Biology 9

2021

Genome editing in food and feed production – implications for risk assessment

Johanna Eva Bodin, Tage Thorstensen, Muath K Alsheikh, Dean Basic, Rolf Brudvik Edvardsen, Knut Tomas Dalen, Carlos Gonçalo das Neves, Nur Duale, Ole Martin Eklo, Åshild Gunilla Ergon, Anne-Marthe Ganes Jevnaker, Kjetil Hindar, Leiv Sigve Håvarstein, Martin Malmstrøm, Kaare Magne Nielsen, Siri Lie Olsen, Eli Knispel Rueness, Monica Sanden, Ville Erling Sipinen, Rose Vikse, Kristine von Krogh, Dag Inge Våge, Anna Wargelius, Micael Wendell, Siamak Pour Yazdankhah, Jan Alexander, Ellen Merete Bruzell, Gro Ingunn Hemre, Vigdis Vandvik, Angelika Agdestein, Edel O. Elvevoll, Dag Olav Hessen, Merete Hofshagen, Trine Husøy, Helle Katrine Knutsen, Åshild Krogdahl, Asbjørn Magne Nilsen, Trond Rafoss, Taran Skjerdal, Inger-Lise Karin Steffensen, Tor Arne Strand, Gaute Velle, Yngvild Wasteson

VKM Report

2021

The salmon louse genome: Copepod features and parasitic adaptations

Rasmus Skern-Mauritzen, Ketil Malde, Christiane Eichner, Michael Dondrup, Tomasz Furmanek, Francois Besnier, Anna Zofia Komisarczuk, Michael Nuhn, Sussie Dalvin, Rolf Brudvik Edvardsen, Sven Klages, Bruno Huettel, Kurt Stueber, Sindre Grotmol, Egil Erlingsson Karlsbakk, Paul Kersey, Jong S Leong, Kevin Alan Glover, Richard Reinhardt, Sigbjørn Lien, Inge Jonassen, Ben F Koop, Frank Nilsen

Genomics 113 p. 3666-3680

2021

Cardiac dysfunction affects eye development and vision by reducing supply of lipids in fish

Elin Sørhus, Sonnich Meier, Carey Donald, Tomasz Furmanek, Rolf Brudvik Edvardsen, Kai Kristoffer Lie

Science of the Total Environment 800

2020

Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon

Hilal Guralp, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Anne Hege Straume, Lene Kleppe, Rüdiger W. Schulz, Rolf Brudvik Edvardsen, Anna Wargelius

Scientific Reports 10

2020

Targeted mutagenesis of Δ5 and Δ6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)

Yang Jin, Alex Kojo Datsomor, Rolf Erik Olsen, Jon Olav Vik, Jacob Seilø Torgersen, Rolf Brudvik Edvardsen, Anna Wargelius, Per Winge, Fabian Grammes

BMC Genomics 21

2020

Autosomal sdY pseudogenes explain discordances between phenotypic sex and DNA marker for sex identification in Atlantic salmon

Fernando Ayllon, Monica Favnebøe Solberg, Francois Besnier, Per Gunnar Fjelldal, Tom Johnny Hansen, Anna Wargelius, Rolf Brudvik Edvardsen, Kevin Glover

Frontiers in Genetics 11 p. 1-10

2020

Comparison of anadromous and landlocked Atlantic salmon genomes reveals signatures of parallel and relaxed selection across the Northern Hemisphere

Erik Nordtorp Kjærner-Semb, Rolf Brudvik Edvardsen, Fernando Ayllon, Petra Vogelsang, Tomasz Furmanek, Carl-Johan Rubin, Alexey E. Veselov, Tom Ole Nilsen, Stephen D. McCormick, Craig R. Primmer, Anna Wargelius

Evolutionary Applications p. 1-16

2020

Transcriptomic analysis of dead end knockout testis reveals germ cell and gonadal somatic factors in Atlantic salmon

Lene Kleppe, Rolf Brudvik Edvardsen, Tomasz Furmanek, Eva Andersson, Kai Ove Skaftnesmo, Frida Thyri Segafredo, Anna Sofie Troedsson Wargelius

BMC Genomics 21 p. 1-15

2020

Indel locations are determined by template polarity in highly efficient in vivo CRISPR/Cas9- mediated HDR in Atlantic salmon

Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Hilal Guralp, Lene Kleppe, Anna Wargelius, Rolf Brudvik Edvardsen

Scientific Reports 10

2020

Microbial communities associated with the parasitic copepod Lepeophtheirus salmonis.

Sussie Dalvin, Kai Ove Skaftnesmo, Ketil Malde, Kevin Glover, Jong S Leong, Ben F. Koop, Rolf Brudvik Edvardsen, Nina Sandlund

Marine Genomics 49

2019

CRISPR/Cas9-mediated editing of Δ5 and Δ6 desaturases impairs Δ8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.)

Alex Kojo Datsomor, Rolf Erik Olsen, Nikola Zic, Angelico Madaro, Atle M. Bones, Rolf Brudvik Edvardsen, Anna Wargelius, Per Winge

Scientific Reports 9 p. 1-13

2019

The initiation of puberty in Atlantic salmon brings about large changes in testicular gene expression that are modulated by the energy status

Diego Crespo, Jan Bogerd, Elisabeth Sambroni, Florence LeGac, Eva Andersson, Rolf Edvardsen, Elisabeth Jonsson Bergman, Björn Thrandur Björnsson, Geir Lasse Taranger, Rüdiger W. Schulz

BMC Genomics 20 p. 1-17

2019

Offshore crude oil disrupts retinoid signaling and eye development in larval Atlantic haddock

Kai Kristoffer Lie, Sonnich Meier, Elin Sørhus, Rolf Edvardsen, Ørjan Karlsen, Pål Asgeir Olsvik

Frontiers in Marine Science 6:368 p. 1-14

2019

Potential of genome editing to improve aquaculture breeding and production

Remi L. Gratacap, Anna Wargelius, Rolf Edvardsen, Ross D. Houston

Trends in Genetics 35 p. 672-684

2019

The influence of vgll3 genotypes on sea age at maturity is altered in farmed mowi strain Atlantic salmon

Fernando Ayllon, Monica Favnebøe Solberg, Kevin Glover, Faezeh Mohammadi, Erik Nordtorp Kjærner-Semb, Per Gunnar Fjelldal, Eva Andersson, Tom Johnny Hansen, Rolf Edvardsen, Anna Wargelius

BMC Genetics 20:44 p. 1-8

2019

CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes

Alex Datsomor, Nikola Zic, Keshuai Li, Rolf Erik Olsen, Yang Jin, Jon Olav Vik, Rolf Edvardsen, Fabian Grammes, Anna Wargelius, Per Winge

Scientific Reports 9 p. 1-13

2018

Genomic architecture of haddock (Melanogrammus aeglefinus) shows expansions of innate immune genes and short tandem repeats

Ole K. Tørresen, Marine Servane Brieuc, Monica Hongrø Solbakken, Elin Sørhus, Alexander Johan Nederbragt, Kjetill Sigurd Jakobsen, Sonnich Meier, Rolf Edvardsen, Sissel Jentoft

BMC Genomics 19 p. 1-17

2018

Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis

Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Lene Kleppe, Elin Sørhus, Kai Ove Skaftnesmo, Tomasz Furmanek, Frida Thyri Segafredo, Anders Thorsen, Per Gunnar Fjelldal, Tom Johnny Hansen, Geir Lasse Taranger, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius, Rolf Edvardsen

Scientific Reports 8:1912 p. 1-11

2017

Integrative testis transcriptome analysis reveals differentially expressed miRNAs and their mRNA targets during early puberty in Atlantic salmon

Kai Ove Skaftnesmo, Rolf Edvardsen, Tomasz Furmanek, D. Crespo, Eva Andersson, Lene Kleppe, Geir Lasse Taranger, Jan Bogerd, Rüdiger W. Schulz, Anna Wargelius

BMC Genomics 18

2017

Sex steroid production associated with puberty is absent in germ cellfree salmon

Lene Kleppe, Eva Andersson, Kai Ove Skaftnesmo, Rolf Edvardsen, Per Gunnar Fjelldal, Birgitta Norberg, Jan Bogerd, Rüdiger W. Schulz, Anna Wargelius

Scientific Reports 7

2017

Susceptibility, behaviour, and retention of the parasitic salmon louse (Lepeophtheirus salmonis) differ with Atlantic salmon population origin

Samantha Bui, Sussie Dalvin, Timothy David Dempster, Ole Fredrik Skulstad, Rolf Edvardsen, Anna Wargelius, Frode Oppedal

Journal of Fish Diseases 41 p. 431-442

2017

An improved genome assembly uncovers prolific tandem repeats in Atlantic cod

Ole Kristian Tørresen, Bastiaan Star, Sissel Jentoft, William Brynildsen Reinar, Harald Grove, Jason R. Miller, Brian Walenz, James Knight, Jenny M. Ekholm, Paul Peluso, Rolf Edvardsen, Ave Tooming-Klunderud, Morten Skage, Sigbjørn Lien, Kjetill Sigurd Jakobsen, Alexander Johan Nederbragt

BMC Genomics 18 p. 1-23

2017

bmp15l, figla, smc1bl, and larp6l are preferentially expressed in germ cells in Atlantic salmon (Salmo salar L.)

Lene Kleppe, Rolf Edvardsen, Tomasz Furmanek, Eva Andersson, Amélie Juanchich, Anna Wargelius

Molecular Reproduction and Development 84 p. 76-87

2017

An improved genome assembly uncovers prolific tandem repeats in Atlantic cod

BMC Genomics 18

2017

Novel adverse outcome pathways revealed by chemical genetics in a developing marine fish

Elin Sørhus, John P. Incardona, Tomasz Furmanek, Giles W. Goetz, Nathaniel Scholz, Sonnich Meier, Rolf Edvardsen, Sissel Jentoft

eLIFE 6:e20707 p. 1-30

2016

Developmental transcriptomics in Atlantic haddock: Illuminating pattern formation and organogenesis in non-model vertebrates

Elin Sørhus, John P. Incardona, Tomasz Furmanek, Sissel Jentoft, Sonnich Meier, Rolf Edvardsen

Developmental Biology 411 p. 301-313

2016

Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon

Anna Wargelius, Sven Dirk Leininger, Kai Ove Skaftnesmo, Lene Kleppe, Eva Andersson, Geir Lasse Taranger, Rüdiger W. Schulz, Rolf Edvardsen

Scientific Reports 6

2016

First feed affects the expressions of microRNA and their targets in Atlantic cod

Teshome Tilahun Bizuayehu, Tomasz Furmanek, Ørjan Karlsen, Terje van der Meeren, Rolf Edvardsen, Ivar Rønnestad, Kristin Hamre, Steinar Daae Johansen, Igor Babiak

British Journal of Nutrition 115 p. 1145-1154

2016

Atlantic salmon populations reveal adaptive divergence of immune related genes - A duplicated genome under selection

Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Vidar Wennevik, Geir Dahle, Eero Niemelä, Mikhail Ozerov, Juha-Pekka Vähä, Kevin Glover, Carl J. Rubin, Anna Wargelius, Rolf Edvardsen

BMC Genomics 17:610 p. 1-12

2016

The two-step development of a duplex retina involves distinct events of cone and rod neurogenesis and differentiation

Ragnhild Valen, Mariann Eilertsen, Rolf Edvardsen, Tomasz Furmanek, Ivar Rønnestad, Terje van der Meeren, Ørjan Karlsen, Tom Ole Nilsen, Jon Vidar Helvik

Developmental Biology 416 p. 389-401

2016

Crude oil exposures reveal roles for intracellular calcium cycling in haddock craniofacial and cardiac development

Elin Sørhus, John P. Incardona, Ørjan Karlsen, Tiffany Linbo, Lisbet Sørensen, Trond Nordtug, Terje van der Meeren, Anders Thorsen, Maja Thorbjørnsen, Sissel Jentoft, Rolf Edvardsen, Sonnich Meier

Scientific Reports 6 p. 1-21

2015

The vgll3 locus controls age at maturity in wild and domesticated Atlantic salmon (Salmo salar L.) males

Ayllon F, Kjærner-Semb E, Furmanek T, Wennevik V, Solberg MF, Dahle G, Taranger GL, Glover KA, Almén MS, Rubin

Plos genetics

2015

The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon(Salmo salar L.) Males

Fernando Ayllon, Erik Nordtorp Kjærner-Semb, Tomasz Furmanek, Vidar Wennevik, Monica Favnebøe Solberg, Geir Dahle, Geir Lasse Taranger, Kevin Glover, Markus Sällman Almén, Carl J. Rubin, Rolf Edvardsen, Anna Wargelius

PLoS Genetics 11:e1005628

2015

A comparison between egg trancriptomes of cod and salmon reveals species-specific traits in eggs for each species

Anna Wargelius, Tomasz Furmanek, Jérôme Montfort, Aurélie Le Cam, Lene Kleppe, Amélie Juanchich, Rolf Edvardsen, Geir Lasse Taranger, Julien Bobe

Molecular Reproduction and Development 82 p. 397-404

2015

Gonad specific genes in Atlantic salmon (Salmon salar L.): Characterization of tdrd7-2, dazl-2, piwil1 and tdrd1 genes

Lene Kleppe, Anna Wargelius, Hanne Johnsen, Eva Andersson, Rolf Edvardsen

Gene 560 p. 217-225

2015

Unexpected interaction with dispersed crude oil droplets drives severe toxicity in atlantic haddock embryos

Elin Sørhus, Rolf Edvardsen, Ørjan Karlsen, Trond Nordtug, Terje van der Meeren, Anders Thorsen, Christopher Peter Harman, Sissel Jentoft, Sonnich Meier

PLOS ONE 10:e0124376 p. 1-21

2015

Diet affects the redox system in developing Atlantic cod (Gadus morhua) larvae

Samuel Penglase, Rolf Edvardsen, Tomasz Furmanek, Ivar Rønnestad, Ørjan Karlsen, Terje van der Meeren, Kristin Hamre

Redox Biology 5 p. 308-318

2014

The exorhodopsin and melanopsin systems in the pineal complex and brain at early developmental stages of Atlantic halibut (Hippoglossus hippoglossus)

Mariann Eilertsen, Øyvind Drivenes, Rolf Edvardsen, Clarissa A. Bradley, Lars O.E. Ebbesson, Jon Vidar Helvik

Journal of Comparative Neurology 522 p. 4003-4022

2014

Molecular evidence that only two opsin subfamilies, the blue light- (SWS2) and green light-sensitive (RH2), drive color vision in Atlantic cod (Gadus morhua).

Ragnhild Valen, Rolf Edvardsen, Anne Mette Søviknes, Øyvind Drivenes, Jon Vidar Helvik

PLOS ONE 9:e0115436

2014

Global transcriptome analysis identifies regulated transcripts and pathways activated during oogenesis and early embryogenesis in atlantic cod

Lene Kleppe, Rolf Edvardsen, Tomasz Furmanek, Geir Lasse Taranger, Anna Wargelius

Molecular Reproduction and Development 81 p. 619-635

2014

Human-induced evolution caught in action: SNP-array reveals rapid amphi-atlantic spread of pesticide resistance in the salmon ecotoparasite Lepeophtheirus salmonis

Francois Besnier, Matthew Peter Kent, Rasmus Skern-Mauritzen, Sigbjørn Lien, Ketil Malde, Rolf Edvardsen, Simon Taylor, Lina Ljungfeldt, Frank Nilsen, Kevin Glover

BMC Genomics

2014

Targeted mutagenesis in Atlantic salmon(Salmo salar L.)Using the CRISPR/Cas9 system induces Complete knockout individuals in the F0 generation

Rolf Edvardsen, Sven Dirk Leininger, Lene Kleppe, Kai Ove Skaftnesmo, Anna Wargelius

PLOS ONE 9 p. 1-7

2014

Gene expression in five salmon louse (Lepeophtheirus salmonis, Krøyer 1837) tissues

Rolf Edvardsen, Sussie Trine Dalvin, Tomasz Furmanek, Ketil Malde, Stig Mæhle, Bjørn Olav Kvamme, Rasmus Skern-Mauritzen

Marine Genomics 18 p. 39-44

2013

Cortisol treatment of prespawning female cod affects cytogenesis related factors in eggs and embryos

Lene Kleppe, Ørjan Karlsen, Rolf Edvardsen, Birgitta Norberg, Eva Andersson, Geir Lasse Taranger, Anna Wargelius

General and Comparative Endocrinology 189 p. 84-95

2013

Effects of oil pollution and persistent organic pollutants (POPs) on glycerophospholipids in liver and brain of male Atlantic cod (Gadus morhua)

Mari Bratberg, Pål Asgeir Olsvik, Rolf Edvardsen, Hans Kristian Brekken, Reidun Vadla, Sonnich Meier

Chemosphere 90 p. 2157-2171

2012

Maternal 3 ' UTRs: from egg to onset of zygotic transcription in Atlantic cod

Lene Kleppe, Rolf Edvardsen, H Kuhl, Ketil Malde, Tomasz Furmanek, O Drivenes, R Reinhardt, Geir Lasse Taranger, Anna Wargelius

BMC Genomics 13

2012

Transcriptomic analyses of intestinal gene expression of juvenile Atlantic cod (Gadus morhua) fed diets with Camelina oil as replacement for fish oil

Sofia Morais, Rolf Edvardsen, Douglas R. Tocher, John Gordon Bell

Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology 161 p. 283-293

2012

Gene Expression Profiling of Atlantic Cod (Gadus morhua) Embryogenesis Using Microarray

Øyvind Drivenes, Geir Lasse Taranger, Rolf Edvardsen

Marine Biotechnology 14 p. 167-176

2011

The genome sequence of Atlantic cod reveals a unique immune system

Bastiaan Star, Alexander Johan Nederbragt, Sissel Jentoft, Unni Grimholt, Martin Malmstrøm, Tone Fredsvik Gregers, Trine Ballestad Rounge, Jonas Paulsen, Monica Hongrø Solbakken, Animesh Sharma, Ola Frang Wetten, Anders Lanzén, Roger Winer, James Knight, Jan-Hinnerk Vogel, Bronwen Aken, Øivind Andersen, Karin Lagesen, Ave Tooming-Klunderud, Rolf Edvardsen, G. Tina Kirubakaran, Mari Espelund, Chirag Nepal, A. Christopher Previti, Bård Ove Karlsen, Truls Moum, Morten Skage, Paul Ragnar Berg, Tor Gjøen, Heiner Kuhl, Jim Thorsen, Ketil Malde, Richard Reinhardt, Lei Du, Steinar Daae Johansen, Steve Searle, Sigbjørn Lien, Frank Nilsen, Inge Jonassen, Stig W Omholt, Nils Christian Stenseth, Kjetill Sigurd Jakobsen

Nature 477 p. 207-210

2011

Four gonadotropin releasing hormone receptor genes in Atlantic cod are differentially expressed in the brain and pituitary during puberty

Jon Hildahl, Guro Katrine Sandvik, Rolf Edvardsen, Birgitta Norberg, Trude M Haug, Finn-Arne Weltzien

General and Comparative Endocrinology 173 p. 333-345

2011

EST resources and establishment and validation of a 16 k cDNA microarray from Atlantic cod (Gadus morhua)

Rolf Edvardsen, Ketil Malde, Christian Mittelholzer, Geir Lasse Taranger, Frank Nilsen

Comparative Biochemistry and Physiology - Part D:Genomics and Proteomics 6 p. 23-30

2011

Identification and gene expression analysis of three GnRH genes in female Atlantic cod during puberty provides insight into GnRH variant gene loss in fish

Jon Hildahl, Guro Katrine Sandvik, Rolf Edvardsen, Cathrine Elisabeth Fagernes, Birgitta Norberg, Trude M Haug, Finn-Arne Weltzien

General and Comparative Endocrinology 172 p. 458-467

2011

RNA deep sequencing of the Atlantic cod transcriptome

Steinar Daae Johansen, Bård Ove Karlsen, Tomasz Furmanek, morten Andreassen, Tor Erik Jørgensen, Teshome Bizuayehu, Ragna Breines, Åse Emblem, Paivi Kettunen, Keijo Luukko, Rolf Edvardsen, Jarle Tryti Nordeide, Dag-Hugo Coucheron, Truls Moum

Comparative Biochemistry and Physiology - Part D:Genomics and Proteomics 6 p. 18-22

2010

Genomic organization and gene expression of the multiple globins in Atlantic cod: conservation of globin-flanking genes in chordates infers the origin of the vertebrate globin clusters

Ola Frang Wetten, Alexander Johan Nederbragt, Robert Wilson, Kjetill Sigurd Jakobsen, Rolf Edvardsen, Øivind Andersen

BMC Evolutionary Biology 10

2010

A case report on the distended gut syndrome (DGS) in cultured larvae of Atlantic cod (Gadus morhua)

Yuko Kamisaka, Ann-Elise Olderbakk Jordal, Rolf Edvardsen, Harald Kryvi, Erling Otterlei, Ivar Rønnestad

Aquaculture 309 p. 38-48

2006

Minimal ProtoHox cluster inferred from bilaterian and cnidarian Hox complements

Daniel Chourrout, Frédéric Delsuc, P Chourrout, Rolf Edvardsen, Fabian Rentzsch, Eduard Renfer, Marit Flo Jensen, Baoli Zhu, Pieter De Jong, Robert E. Steele, Ulrich Technau

Nature 442 p. 684-687

2005

Remodelling of the homeobox gene complement in the tunicate Oikopleura dioica

Rolf Edvardsen, Hee-Chan Seo, Marit Flo Jensen, Antoine Mialon, Iana Mikhaleva, Marianne Bjørdal, Jerome Cartry, Richard Reinhardt, Jean Weissenbach, Patric Wincker, Daniel Chourrout

Current Biology 15 p. 12-13

2004

Hox cluster disintegration with persistent anteroposterior order of expression in Oikopleura dioica

Hee-Chan Seo, Rolf Edvardsen, Anne Dorthea Mæland, Marianne Bjørdal, Marit Flo Jensen, Anette H. Hansen, Mette Flåt, Jean Weissenbach, Hans Lehrach, Patric Wincker, Richard Reinhardt, Daniel Chourrout

Nature 431 p. 67-71

2004

Hypervariable and Highly Divergent Intron/Exon Organizations in The Chordate Oikopleura dioica

Rolf Edvardsen, Emanuelle Lerat, Anne Dorthea Mæland, Mette Flåt, Rita Tewari, Marit Flo Jensen, Hans Lehrach, Richard Reinhardt, Hee-Chan Seo, Daniel Chourrout

Journal of Molecular Evolution 59 p. 448-457

2003

Urochordates carry multiple genes for goose-type lysozyme and no genes for chicken- or invertebrate-type lysozymes

Inge Waller Nilsen, Bjørnar Myrnes, Rolf Edvardsen, Daniel Chourrout

Cellular and Molecular Life Sciences (CMLS) 60 p. 2210-2218

2001

Miniature genome in the marine chordate Oikopleura dioica

Hee-Chan Seo, M Kube, Rolf Edvardsen, Marit Flo Jensen, A Beck, Endy Spriet, Gabriel Gorsky, Eric Thompson, Hans Lehrach, Richard Reinhardt, Daniel Chourrout

Science 294 p. 2506

Other journal contributions

2021

Author Correction: Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon (Scientific Reports, (2020), 10, 1, (18042), 10.1038/s41598-020-74876-2)

Hilal Güralp, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Anne Hege Straume, Lene Kleppe, Rüdiger W. Schulz, Rolf Brudvik Edvardsen, Anna Wargelius

Scientific Reports 11

2016

Ulik laks i sør og nord

Erik Nordtorp Kjærner-Semb, Anna Wargelius, Rolf Edvardsen

Dagens næringsliv

Scientific lectures

2024

Transkriptomikk og genredigering som verktøy for å utforske genetiske mekanismer som kan gi artsspesifkk resistens mot lakselus

Mette Serine Wesmajervi Breiland, Nicholas Andrew Robinson, Tone-Kari K Østbye, Sarah Salisbury, Lene Sveen, Mark Fast, Aleksei Krasnov, R.R Daniels, Torstein Tengs, Rolf Brudvik Edvardsen, Erik Nordtorp Kjærner-Semb, Teshome Bizuayehu, S.J. Monaghan, Aina-Cathrine Øvergård, Helena Marie Doherty Midtbø, H.M. Bron, Anna Wargelius, Matthew Daniel Baranski, R. Houston, D. Robledo

2024

Use of transcriptomics and gene editing to explore genetic mechanisms giving species-specific host-resistance to sea lice

Nicholas Andrew Robinson, Tone-Kari K Østbye, Sarah Salisbury, Lene Sveen, Mark D. Fast, Aleksei Krasnov, Rose Ruiz Daniels, Torstein Tengs, Rolf Brudvik Edvardsen, Erik Nordtorp Kjærner-Semb, Teshome Bizuayehu, Sean J. Monaghan, Aina-Cathrine Øvergård, Helena Marie Doherty Midtbø, James E. Bron, Anna Wargelius, Matthew Daniel Baranski, Ross D. Houston, Diego Robledo

2024

Uses of biotechnology to control reproduction in Atlantic salmon

Lene Kleppe, Anna Sofie Troedsson Wargelius, Diego Crespo, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Eva Andersson, Per Gunnar Fjelldal, Tom Johnny Hansen, Rolf Brudvik Edvardsen, Anders Thorsen, Rüdiger W. Schulz, Anne Torsvik, Grethe Beate Thorsheim, Anne Hege Straume, Petra Vogelsang, Ivar Helge Matre, Ann-Kathrin Jakobsen Kroken, Lise Dyrhovden, Audun Østby Pedersen, Simon Flavell, Florian Sambraus, Arnor Gullanger, Tone Knappskog

2024

Moving sterile Crispr salmon from the tank to sea cages - regulatory barriers and social impacts

Anna Sofie Troedsson Wargelius, Erik Nordtorp Kjærner-Semb, Anne Hege Straume, Per Gunnar Fjelldal, Jonatan Nilsson, Hilal Guralp, Kai Ove Skaftnesmo, Dorothy Jane Dankel, Eva Andersson, Lene Kleppe, Rolf Brudvik Edvardsen

2023

Integration of Comparative Genomics with CRISPR: Applications for sea lice resistance Integration of Comparative Genomics with CRISPR: Applications for sea lice resistance.

Mark D. Fast, Tone-Kari K Østbye, Aleksei Krasnov, Sarah Salisbury, Rose Ruiz Daniels, Davila Soto, Lene Sveen, Rolf Brudvik Edvardsen, Teshome Bizuayehu, Ross D. Houston, Nicholas Andrew Robinson, Diego Robledo

2022

Towards a greater understanding of crude oil induced eye abnormalities

Elin Sørhus, Sonnich Meier, Carey Donald, Prescilla Perrichon, Tomasz Furmanek, Rolf Brudvik Edvardsen, Kai Kristoffer Lie

2022

VGLL3A ALLELES AFFECT THE BRAIN-PITUITARY-GONAD AXIS IN ATLANTIC SALMON (SALMO SALAR) VIA REGULATION OF FSHB

Diego Crespo, Per Gunnar Fjelldal, Thomas Fraser, Rolf Brudvik Edvardsen, Anna Sofie Troedsson Wargelius

2022

Photoreception and transcriptome response to light during early development of Atlantic salmon (Salmon salar)

Mariann Eilertsen, David William Peter Dolan, Charlotte M. Bolton, Rita Karlsen, Wayne I. L. Davies, Rolf Brudvik Edvardsen, Tomasz Furmanek, Harald Sveier, Hervé Migaud, Jon Vidar Helvik

2020

Hva er de genetiske forskjellene mellom ferskvannslaks og anadrom laks?.

Erik Nordtorp Kjærner-Semb, Rolf Brudvik Edvardsen, Fernando Ayllon, Tomasz Furmanek, Carl Johan Rubin, Tom Ole Nilsen, Vidar Wennevik, Craig Primmer, Anna Sofie Troedsson Wargelius

2019

Genomic regions under selection in landlocked Atlantic salmon. International Conference on Integrative Salmonid Biology

Erik Nordtorp Kjærner-Semb, Rolf Brudvik Edvardsen, Fernando Ayllon, Tomasz Furmanek, Carl-Johan Rubin, Vidar Wennevik, Tom Ole Nilsen, Craig Primmer, Anna Sofie Troedsson Wargelius

2019

Highly efficient CRISPR/Cas9 knock-in in Atlantic salmon

Rolf Brudvik Edvardsen, Anne Hege Straume, Erik Nordtorp Kjærner-Semb, hilal guralp, Lene Kleppe, Kai Ove Skaftnesmo, Anna Wargelius

2019

CRISPR Salmon - a step towards sustainable aquaculture

Edvardsen, Rolf Brudvik

2019

CRISPR - muligheter for bærekraftig akvakultur

Edvardsen, Rolf Brudvik

2019

CRISPR - og muligheter i oppdrett

Edvardsen, Rolf Brudvik

2019

Geneditering i laks – en mulighet for bærekraftig akvakultur

Edvardsen, Rolf Brudvik

2019

CRISPR – Teknologi for bærekraftig oppdrett

Edvardsen, Rolf Brudvik

2019

Highly efficient CRISPR/Cas9 knock-in in Atlantic Salmon

Anne Hege Straume, hilal guralp, Kai Ove Skaftnesmo, Anna Wargelius, Rolf Brudvik Edvardsen

2019

Genomic regions under selection in landlocked Atlantic salmon

Erik Nordtorp Kjærner-Semb, Rolf Brudvik Edvardsen, Fernando Ayllon, Tomasz Furmanek, Carl Johan Rubin, Vidar Wennevik, Tom Ole Nilsen, Stephen McCormic, Craig Primmer, Anna Wargelius

2018

Susceptibility to salmonid alphavirus (SAV) of different salmon breed lines.

Noelia Nuñez-Ortiz, Rasmus Skern-Mauritzen, Stig Mæhle, Lindsey Moore, Tom Johnny Hansen, Per Gunnar Fjelldal, Tomasz Furmanek, Rolf Edvardsen, Samuel A. M. Martin, Sonal Patel

2018

Hvordan fungerer laksens pubertetsgen?

2018

The interbrancheal lymphoid tissue (ILT) of salmonid fish: How to be classified?

Erling Olaf Koppang, Ida Bergva Aas, Rolf Edvardsen, Tomasz Furmanek, Lars Austbø

2018

Geneditering i laks – en mulighet for bærekraftig akvakultur

Edvardsen, Rolf

2018

Optimization of CRISPR/Cas9 knock-in technology and application in salmon

Rolf Edvardsen, Anne Hege Straume, Kai Ove Skaftnesmo, Lene Kleppe, hilal guralp, Anna Wargelius

2018

Det interbrankiale lymfoide vevet, et unikt lymfoid vev i gjelle hos Atlantisk laks

Lars Austbø, Ida Bergva Aas, Rolf Edvardsen, Tomasz Furmanek, Erling Olaf Koppang

2018

RNA-Seq reveals novel impacts of PAHs on excitation-transcription coupling in cardiomyocytes

Elin Sørhus, Sonnich Meier, John P. Incardona, Rolf Edvardsen, Tomasz Furmanek

2017

A comparative study of diploid and triploid Atlantic salmon post-smolts upon SAV-3 bath challenge and their immune transcriptomatic responses

Noelia Nuñez-Ortiz, Lindsey Moore, Tomasz Furmanek, Rolf Edvardsen, Samuel A. M. Martin, Tom Ole Nilsen, Jiraporn Jarungsriapisit, Per Gunnar Fjelldal, Sigurd Olav Stefansson, Geir Lasse Taranger, Sonal Patel

2017

Geneditering i laks – en mulighet for bærekraftig akvakultur

Edvardsen, Rolf

2017

Geneditering i laks – en mulighet for bærekraftig akvakultur

Edvardsen, Rolf

2016

Er atferd hos oppdrettslaks familieavhengig?

Ole Folkedal, Lars Helge Stien, Jonatan Nilsson, Thomas Torgersen, Jan Erik Fosseidengen, Rolf Edvardsen, Tore S Kristiansen

2016

Targeting germ cell survival factors to produce sterile salmon

Lene Kleppe, Anna Wargelius, Helge Tveiten, Sven Dirk Leininger, Kai Ove Skaftnesmo, Tomasz Furmanek, Rüdiger W. Schulz, Geir Lasse Taranger, Eva Andersson, Rolf Edvardsen

2016

Targeting germ cell survival factors to produce sterile salmon through vaccination

Lene Kleppe, Anna Wargelius, Helge Tveiten, Sven Dirk Leininger, Kai Ove Skaftnesmo, Tomasz Furmanek, Rüdiger W. Schulz, Geir Lasse Taranger, Eva Andersson, Rolf Edvardsen

2016

Sterile salmon by targeting factors involved in germ cell survival: novel strategies for sustainable fish farming

Lene Kleppe, Rolf Edvardsen, Helge Tveiten, Sven Dirk Leininger, Kai Ove Skaftnesmo, Eva Andersson, Geir Lasse Taranger, Rüdiger W. Schulz, Tomasz Furmanek, Anna Wargelius

2016

Genomic revolution – How the new technology is applied and changes everything

Edvardsen, Rolf

2016

Targeted mutagenesis in Atlantic salmon using the CRISPR/Cas9 system

Rolf Edvardsen, Lene Kleppe, Kai Ove Skaftnesmo, Sven Dirk Leininger, Tomasz Furmanek, Geir Lasse Taranger, Rüdiger W. Schulz, Eva Andersson, Anna Wargelius

2016

Bruk av CRISPR/Cas9 i laks

Rolf Edvardsen, Lene Kleppe, Kai Ove Skaftnesmo, Sven Dirk Leininger, Tomasz Furmanek, Geir Lasse Taranger, Rüdiger W. Schulz, Eva Andersson, Anna Wargelius

2016

Genome resequencing of geographically distinct Atlantic Salmon (Salmo salar) populations reveals adaptive divergence

Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Vidar Wennevik, Geir Dahle, Eero Niemelä, Mikhail Ozerov, Juha-Pekka Vähä, Kevin Glover, Carl Johan Rubin, Anna Wargelius

2016

Adaptive plasticity in Atlantic salmon- genetic predisposition of time at maturity and environmental triggers

Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Tom Johnny Hansen, Per Gunnar Fjelldal, Carl Johan Rubin, Lene Kleppe, Kai Ove Skaftnesmo, Elin Sørhus, Faezeh Mohammadi, Geir Dahle, Vidar Wennevik, Monica Favnebøe Solberg, Kevin Glover, Birgitta Norberg, Geir Lasse Taranger, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius

2016

Transcriptomics identifies novel adverse outcome pathways from crude oil exposure in haddock early life history stages

Elin Sørhus, John P. Incardona, Tomasz Furmanek, Nathaniel Scholz, Sonnich Meier, Sissel Jentoft, Rolf Edvardsen

2016

Fleshing out crude oil cardiotoxicity adverse outcome pathways with transcriptomics in Atlantic haddock embryos

Elin Sørhus, John P. Incardona, Tiffany Linbo, Lisbet Sørensen, Trond Nordtug, Terje van der Meeren, Anders Thorsen, Sissel Jentoft, Rolf Edvardsen, Sonnich Meier

2016

Transcriptomics identifies novel adverse outcome pathways from crude oil exposure in haddock early life history stages

Sørhus Elin, Incardona John, Tomasz Furmanek, Nathaniel Scholz, Sonnich Meier, Sissel Jentoft, Rolf Edvardsen

2015

Linking mechanisms of PAH cardiotoxicity, morphogenetic defects and cardiac gene expression in atlantic haddock

Elin Sørhus, Rolf Edvardsen, Ørjan Karlsen, Lisbet Sørensen, Trond Nordtug, Terje van der Meeren, Anders Thorsen, Sissel Jentoft, John Incardona, Frode Bendiksen Vikebø, Maja Thorbjørnsen, Sonnich Meier

2014

A comparison between egg trancriptomes of cod and salmon reveals species specific traits in eggs for each species

Anna Wargelius, Tomasz Furmanek, Jerome Montfort, Aurelie Le Cam, Lene Kleppe, Rolf Edvardsen, Geir Lasse Taranger, Julien Bobe

2014

APPLICATIONS OF GENOME-WIDE TECHNIQUES TO STUDY SALMON PHYSIOLOGY, DEVELOPMENT AND REPRODUCTION

Geir Lasse Taranger, Rolf Edvardsen, Lene Kleppe, Eva Andersson, Anna Wargelius

2014

Interactions between pelagic fish embryos and dispersed oil droplets

Elin Sørhus, Sonnich Meier, Anders Thorsen, Rolf Edvardsen, Sissel Jentoft, Trond Nordtug, Domagoj Maksan, Maja Thorbjørnsen, Christopher Peter Harman, Terje van der Meeren, Ørjan Karlsen

2014

Characterizing appetite controlling system in fast-growing Atlantic cod larvae

Ivar Rønnestad, Anna Rita Angotzi, M.T.D Hoang Le, Rolf Edvardsen, Lars O.E. Ebbesson, Augustine Arukwe, Ørjan Karlsen, Terje van der Meeren, Knut Helge Jensen, Ann-Elise Olderbakk Jordal

2014

Hva karakteriserer fysiologiske systemer som kontrollerer apetitt og fordøyelse i rasktvoksende torskelarver

Ann-Elise Olderbakk Jordal, Rolf Edvardsen, Anna Rita Angotzi, M.T.D Hoang Le, Ørjan Karlsen, Terje van der Meeren, Ivar Rønnestad

2014

Interaction between pelagic fish embryos and dispersed oil droplets

Elin Sørhus, Rolf Edvardsen, Ørjan Karlsen, Trond Nordtug, Terje van der Meeren, Anders Thorsen, Domagoj Maksan, Maja Thorbjørnsen, Christopher Peter Harman, Sissel Jentoft, Sonnich Meier

2014

Interactions between pelagic fish embryos and dispersed oil droplets

Sørhus Elin, Rolf Edvardsen, Ørjan Karlsen, Trond Nordtug, Terje van der Meeren, Anders Thorsen, Domagoj Maksan, Maja Thorbjørnsen, Christopher Peter Harman, Sissel Jentoft, Sonnich Meier

2014

Transkriptomanalyse av atlantisk torsk - mekanismer for rask vekst

Rolf Edvardsen, Tomasz Furmanek, Teshome Bizauyehu, Igor Babiak, Matilde Skogen Chauton, Kai Kristoffer Lie, Ann-Elise Olderbakk Jordal, Elin Sørhus, Ørjan Karlsen, Terje van der Meeren, Anders Mangor-Jensen, Ivar Rønnestad

2013

GLOBAL TRANSCRIPTOME ANALYSIS IDENTIFIES REGULATED TRANSCRIPTS AND PATHWAYS ACTIVATED DURING OOGENESIS AND EARLY EMBRYOGENESIS IN ATLANTIC COD

Lene Kleppe, Rolf Edvardsen, Tomasz Furmanek, Geir Lasse Taranger, Anna Wargelius

2013

GLOBAL AND LOCAL METHYLATION PATTERN IN TRIPLOID AND DIPLOID AND TRIPLOID ATLANTIC SALMON

Anna Wargelius, Tomasz Furmanek, Rolf Edvardsen, Elin Sørhus, Per Gunnar Fjelldal, Tom Johnny Hansen

2013

TRANSCRIPTOMIC ANALYSIS OF DEVELOPING ATLANTIC COD - UNDERSTANDING THE MECHANISMS UNDERLYING HIGH GROWTH

Rolf Edvardsen, Tomasz Furmanek, Kai Kristoffer Lie, Ann-Elise Olderbakk Jordal, Elin Sørhus, Ørjan Karlsen, Terje van der Meeren, Anders Mangor-Jensen, Ivar Rønnestad

2013

Transcriptome analysis- monitoring dietary effects on appetite and digestion in Atlantic cod larvae during ontogeny

Ann-Elise Olderbakk Jordal, Rolf Edvardsen, Anna Rita Angotzi, M.T.D. Le, Ørjan Karlsen, Terje van der Meeren, Ivar Rønnestad

2012

Attempts to induce sterility in Atlantic salmon by morfolino and zink finger techniques

Anna Wargelius, Rolf Edvardsen, Trine Haugen, Ståle Ellingsen, Eva Andersson, Ketil Malde, Ørjan Karlsen, Per Gunnar Fjelldal, Geir Lasse Taranger, Øyvind Drivenes

2012

Knockdown of salmon dead-end affect gonad morphology in 10 months old Atlantic salmon (Salmo Salar L.)

Anna Wargelius, Øyvind Drivenes, Trine Haugen, Per Gunnar Fjelldal, Eva Andersson, Hans-Øyvind Svensvik, Rolf Edvardsen, Geir Lasse Taranger

2012

Transcriptomic analysis of the salmon louse

Rolf Edvardsen, Stig Mæhle, Tomasz Furmanek, Ketil Malde, Bjørn Olav Kvamme, Sussie Trine Dalvin, Rasmus Skern-Mauritzen

2011

Maternal 3'UTRs: from egg to onset of zygotic transcription in Atlantic cod

Lene Kleppe, Rolf Edvardsen, Heiner Kuhl, Ketil Malde, Tomasz Furmanek, Øyvind Drivenes, Richard Reinhardt, Geir Lasse Taranger, Anna Wargelius

Poster

2022

REGULATION OF GENE EXPRESSION LEVELS BY 3’UTR MODIFICATION

Mari Raudstein, Morten Barvik, Rolf Brudvik Edvardsen, Ståle Ellingsen

2021

Long-term performance of gene edited, sterile Atlantic salmon - growth, smoltification, welfare indicators and fillet composition.

Lene Kleppe, Per Gunnar Fjelldal, Eva Andersson, Tom Johnny Hansen, Monica Sanden, Aina Bruvik, Kai Ove Skaftnesmo, Tomasz Furmanek, Erik Nordtorp Kjærner-Semb, Diego Crespo, Simon Flavell, Audun Ø. Pedersen, Petra Vogelsang, Anne Torsvik, Sara Olausson, Birgitta Norberg, Rüdiger W. Schulz, Jan Bogerd, Nina Santi, Rolf Brudvik Edvardsen, Anna Wargelius

2019

Exploring beneficial genetic variants in Atlantic salmon using gene editing

Erik Nordtorp Kjærner-Semb, Anna Wargelius, Rolf Brudvik Edvardsen

2018

VGLL3 AND THE HIPPO PATHWAY ARE REGULATED IN SERTOLI CELLS UPON ENTRY AND DURING PUBERTY IN ATLANTIC SALMON TESTIS.

2018

Features of the interbrancheal lymphoid tissue (ILT) in the Atlantic salmon

Lars Austbø, Ida Bergva Aas, Rolf Edvardsen, Tomasz Furmanek, Erling Olaf Koppang

2017

ARE SWIMMING DEPTH PREFERENCES IN FARMED ATLANTIC SALMON GENETICALLY DEPENDENT?

Ole Folkedal, Lars Helge Stien, Ingunn Thorland, Rudi Ripman Seim, Roy Hjelmeland, Thomas Torgersen, Jonatan Nilsson, Rolf Edvardsen, Morten Rye, Håvard Bakke, Øyvind Øverli, Tore S Kristiansen

2015

Diet affects the redox system in developing Atlantic cod (Gadus morhua) larvae

Kristin Hamre, Samuel Penglase, Rolf Edvardsen, Tomasz Furmanek, Ørjan Karlsen, Terje van der Meeren, Ivar Rønnestad

2015

SCREENING FOR STERILITY CANDIDATE GENES IN ATLANTIC SALMON (SALMO SALAR)

Lene Kleppe, Rolf Edvardsen, Tomasz Furmanek, Eva Andersson, Anna Wargelius

2014

Candidate genes for sterility in Atlantic salmon (Salmo salar)

Lene Kleppe, Anna Wargelius, Eva Andersson, Geir Lasse Taranger, Rolf Edvardsen

2014

SMALL RNAS IN IMMATURE AND MATURE TESTIS OF ATLANTIC SALMON (SALMO SALAR L.)

Kai Ove Skaftnesmo, Rolf Edvardsen, Tomasz Furmanek, Eva Andersson, Lene Kleppe, Jan Bogerd, Rüdiger W. Schulz, Geir Lasse Taranger, Anna Wargelius

2012

Hypothalamic and pituitary factors controlling reproduction in Atlantic salmon

Jan Bogerd, H.F. Vischer, Rolf Edvardsen, Eva Andersson, Jean-Jacques Lareyre, Geir Lasse Taranger, Rüdiger W. Schulz

2011

The link between broodstock stress and offspring developmental potential in Atlantic cod Gadus morhua L

Lene Kleppe, Ørjan Karlsen, Rolf Edvardsen, Øyvind Drivenes, Birgitta Norberg, Geir Lasse Taranger, Anna Wargelius

Reports and dissertations

2017

DNA damage and health effects in juvenile haddock exposed to sediment or produced water associated PAHs

Sonnich Meier, Ørjan Karlsen, Jérémie Le Goff, Lisbet Sørensen, Rolf Edvardsen, Sissel Jentoft, Karianne Skogland, Per Gunnar Fjelldal, Daniela Maria Pampanin, Evgenia Dunaevskaya, Marta Romano, Mark Myers, Bjørn Einar Grøsvik

2017

Genetics behind puberty and adaptation in Atlantic Salmon revealed by genomic studies

Anna Wargelius, Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Kevin Glover

2015

Endrer gener for å få steril fisk

Anna Wargelius, Rolf Edvardsen

2014

Sekvensering av havet – fremtidens teknologi

Nina Sandlund, Sussie Trine Dalvin, Aina-Cathrine Øvergård, Rolf Edvardsen

2005

Rapid genome evolution in the urochordate lineage of Oikopleura dioica

Rolf Edvardsen, Daniel Chourrout

1998

Analysis of DNA-binding properties of the Zebrafish Pax6 protein and its possible involvement in autoregulation

Edvardsen, Rolf

News

(15.03.2022) Researchers identify the halibut’s sex gene

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