2022
Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars)
Sofie Søderstrøm, Roger Lille-Langøy, Fekadu Yadetie, Mateusz Rauch, Ana Milinski, Annick Dejaegere, Roland H Stote, Anders Goksøyr, Odd André Karlsen
Environment International
163:107203
p. 1-15
2022
Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes
Anneli Strobel, Roger Lille-Langøy, Helmut Segner, Patricia Burkhardt-Holm, Anders Goksøyr, Odd André Karlsen
Polar Biology
45
p. 345-358
2021
Substituted Two- to Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a
Roger Lille-Langøy, Kåre Bredeli Jørgensen, Anders Goksøyr, Daniela M Pampanin, Magne O Sydnes, Odd André Karlsen
Environmental Science & Technology
55
p. 15123-15135
2021
Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro
Siri Øfsthus Goksøyr, Jed Goldstone, Roger Lille-Langøy, Erik-Jan Lock, Pål A Olsvik, Anders Goksøyr, Odd André Karlsen
Aquatic Toxicology
238:105914
p. 1-11
2020
Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua)
Karina Dale, Fekadu Yadetie, Mette Bjørge Müller, Daniela M Pampanin, Alejandra Gilabert, Xiaokang Zhang, Zhanna Tairova, Ane Haarr, Roger Lille-Langøy, Jan Ludvig Lyche, Cinta Porte, Odd André Karlsen, Anders Goksøyr
Aquatic Toxicology
227:105590
p. 1-13
2020
Environmental Pollutants Modulate Transcriptional Activity of Nuclear Receptors of Whales In Vitro
Katharina Lühmann, Roger Lille-Langøy, Lene Øygarden, Kit M Kovacs, Christian Lydersen, Anders Goksøyr, Heli Routti
Environmental Science & Technology
54
p. 5629-39
2020
Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a
Libe Aranguren-Abadía, Roger Lille-Langøy, Alexander K Madsen, Sibel I Karchner, Diana G Franks, Fekadu Yadetie, Mark E Hahn, Anders Goksøyr, Odd André Karlsen
Environmental Science & Technology
54
p. 1033-44
2019
Modulation of Neuro-Dopamine Homeostasis in Juvenile Female Atlantic Cod ( Gadus morhua) Exposed to Polycyclic Aromatic Hydrocarbons and Perfluoroalkyl Substances
Essa A Khan, Luisa B Bertotto, Karina Dale, Roger Lille-Langøy, Fekadu Yadetie, Odd André Karlsen, Anders Goksøyr, Daniel Schlenk, Augustine Arukwe
Environmental Science & Technology
53
p. 7036-44
2019
Environmental contaminants modulate the transcriptional activity of polar bear (Ursus maritimus) and human peroxisome proliferator-activated receptor alpha (PPARA)
Heli Routti, Mari K Berg, Roger Lille-Langøy, Lene Øygarden, Mikael Harju, Rune Dietz, Christian Sonne, Anders Goksøyr
Scientific reports
6:6918
p. 1-14
2019
Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway
Karina Dale, Mette Bjørge Müller, Zhanna Tairova, Essa Ahsan Khan, Kristin Hatlen, Merete Grung, Fekadu Yadetie, Roger Lille-Langøy, Nello Blaser, Hans J Skaug, Jan Ludvig Lyche, Augustine Arukwe, Ketil Hylland, Odd André Karlsen, Anders Goksøyr
Marine Environmental Research
145
p. 39-51
2019
Sequence Variations in pxr (nr1i2) From Zebrafish (Danio rerio) Strains Affect Nuclear Receptor Function
Roger Lille-Langøy, Odd André Karlsen, Line Merethe Myklebust, Jared V Goldstone, Astrid Mork-Jansson, Rune Male, Bruce Blumberg, John J Stegeman, Anders Goksøyr
Toxicological Sciences
168
p. 28-39
2018
Independent losses of a xenobiotic receptor across teleost evolution
Marta Eide, Halfdan Rydbeck, Ole K Tørresen, Roger Lille-Langøy, Pål Puntervoll, Jared V Goldstone, Kjetill S Jakobsen, John Stegeman, Anders Goksøyr, Odd A Karlsen
Scientific Reports
8:10404
p. 1-13
2018
Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays
Maria Blanco, Elisabet Pérez-Albaladejo, Benjamí Piña, Grozdan Kušpilić, Vesna Milun, Roger Lille-Langøy, Odd André Karlsen, Anders Goksøyr, Cinta Porte
Science of the Total Environment
15:624
p. 1640-1648
2017
Multiple-stressor effects in an apex predator: combined influence of pollutants and sea ice decline on lipid metabolism in polar bears
Sabrina Tartu, Roger Lille-Langøy, Trond R Størseth, Sophie Bourgeon, Anders Brunsvik, Jon Aars, Anders Goksøyr, Bjørn Munro Jenssen, Anuschka Polder, Gregory W Thiemann, Vidar Torget, Heli Routti
Scientific Reports
7:16487
p. 1-12
2016
Environmental Chemicals Modulate Polar Bear (Ursus maritimus) Peroxisome Proliferator-Activated Receptor Gamma (PPARG) and Adipogenesis in Vitro
Heli Routti, Roger Lille-Langøy, Mari K Berg, Trine Fink, Mikael Harju, Kurt Kristiansen 5, Pawel Rostkowski, Marte Rusten, Ingebrigt Sylte, Lene Øygarden , Anders Goksøyr
Environmental Science & Technology
50(19)
p. 10708-10720
2016
Assessment of the environmental quality of coastal sediments by using a combination of in vitro bioassays
Elisabet Pérez-Albaladejo, Juliane Rizzi, Denise Fernandes, Roger Lille-Langøy, Odd André Karlsen, Anders Goksøyr, Andra Oros, Federico Spagnoli, Cinta Porte
Marine Pollution Bulletin
108(1-2)
p. 53-61
2015
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently
Roger Lille-Langøy, Jared V Goldstone, Marte Rusten, Matthew R Milnes, Rune Male, John J Stegeman, Bruce Blumberg, Anders Goksøyr
Toxicology and Applied Pharmacology
284
p. 54-64
2013
Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio)
Afonso C D Bainy , Akira Kubota, Jared V Goldstone, Roger Lille-Langøy, Sibel I Karchner, Malin C Celander, Mark E Hahn, Anders Goksøyr, John J Stegeman
Aquatic Toxicolgy
142-143
p. 447-57