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Havforskningsinstituttet HI Åpne/Lukke hovedmeny
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Erik Kjærner-Semb

erik3
Forsker
Telefon: 93815437
Avdeling: Reproduksjon og utviklingsbiologi

Jobber som forsker i forskningsgruppen for Reproduksjon og Utviklingsbiologi, med hovedfokus studier av laksens gener og DNA. Arbeidet er spesielt rettet mot gener som styrer kjønnsmodning og gener som kan bidra til at laksen får et bedre liv.

Arbeidsområde

Arbeidsområde

Molekylærbiologi og bioinformatikk

Curriculum Vitae

Curriculum Vitae

Siv.ing. i Molekylær Bioteknologi / MSc in Molecular Biotechnology.

PhD i Molekylærbiologi.

ResearchGate profile: https://www.researchgate.net/profile/Erik_Kjaerner-Semb

Publikasjoner

Publikasjoner

Vitenskapelige artikler (NVI)

2024

Adaptation in landlocked Atlantic salmon links genetics in wild and farmed salmon to smoltification

Ross Fisher Cairnduff, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Monica Favnebøe Solberg, Eva Andersson, Craig Primmer, William Perry, Kevin Alan Glover, Anna Sofie Troedsson Wargelius
BMC Genomic Data 25
2024

Loss of bmp15 function in the seasonal spawner Atlantic salmon results in ovulatory failure

Diego Crespo, Per Gunnar Fjelldal, Tom Johnny Hansen, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Anders Thorsen, Birgitta Norberg, Rolf Brudvik Edvardsen, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius, Lene Kleppe
The FASEB Journal 38
2024

Highly efficient in vivo C-to-T base editing in Atlantic salmon (Salmo salar) – A step towards aquaculture precision breeding

Mari Torsdotter Raudstein, Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Morten Barvik, Ståle Ellingsen, Rolf Brudvik Edvardsen
Aquaculture 581
2024

Loss of Fshr Prevents Testicular Maturation in Atlantic Salmon (Salmo salar L.)

Eva Andersson, Rüdiger W. Schulz, Fernanda Almeida, Lene Kleppe, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Diego Crespo, Per Gunnar Fjelldal, Tom Johnny Hansen, Birgitta Norberg, Rolf Brudvik Edvardsen, Anna Wargelius
Endocrinology 165
2023

In vivo CRISPR/LbCas12a-mediated knock-in and knock-out in Atlantic salmon (Salmo salar L.)

Mari Torsdotter Raudstein, Erik Nordtorp Kjærner-Semb, Morten Barvik, Silje Broll, Anne Hege Straume, Rolf Brudvik Edvardsen
Transgenic research
2022

Heterochiasmy and the establishment of gsdf as a novel sex determining gene in Atlantic halibut

Rolf Brudvik Edvardsen, Ola Wallerman, Tomasz Furmanek, Lene Kleppe, Patric Jern, Andreas Wallberg, Erik Nordtorp Kjærner-Semb, Stig Mæhle, Sara Olausson, Elisabeth Sundström, Torstein Harboe, Ragnfrid Mangor-Jensen, Margareth Møgster Drønen, Prescilla Perrichon, Birgitta Norberg, Carl-Johan Rubin
PLoS Genetics 18
2022

Pituitary Gonadotropin Gene Expression During Induced Onset of Postsmolt Maturation in Male Atlantic Salmon: In Vivo and Tissue Culture Studies

Diego Crespo, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Ozlem Yilmaz, Birgitta Norberg, Sara Olausson, Petra Vogelsang, Jan Bogerd, Lene Kleppe, Rolf Brudvik Edvardsen, Eva Andersson, Anna Wargelius, Tom Johnny Hansen, Per Gunnar Fjelldal, Rüdiger W. Schulz
Frontiers in Endocrinology 13
2022

Full production cycle performance of gene-edited, sterile Atlantic salmon - growth, smoltification, welfare indicators and fillet composition

Lene Kleppe, Per Gunnar Fjelldal, Eva Andersson, Tom Johnny Hansen, Monica Sanden, Aina Bruvik, Kai Ove Skaftnesmo, Tomasz Furmanek, Erik Nordtorp Kjærner-Semb, Diego Crespo, Simon Flavell, Audun Østby Pedersen, Petra Vogelsang, Anja Torsvik, Karen Anita Kvestad, Sara Olausson, Birgitta Norberg, Rüdiger W. Schulz, J. Bogerd, N. Santi, Rolf Brudvik Edvardsen, Anna Wargelius
Aquaculture 560
2021

Single nucleotide replacement in the Atlantic salmon genome using CRISPR/Cas9 and asymmetrical oligonucleotide donors

Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Hilal Guralp, Simon Lillico, Anna Wargelius, Rolf Brudvik Edvardsen
BMC Genomics 22
2020

Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon

Hilal Guralp, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Anne Hege Straume, Lene Kleppe, Rüdiger W. Schulz, Rolf Brudvik Edvardsen, Anna Wargelius
Scientific Reports 10
2020

Comparison of anadromous and landlocked Atlantic salmon genomes reveals signatures of parallel and relaxed selection across the Northern Hemisphere

Erik Nordtorp Kjærner-Semb, Rolf Brudvik Edvardsen, Fernando Ayllon, Petra Vogelsang, Tomasz Furmanek, Carl-Johan Rubin, Alexey E. Veselov, Tom Ole Nilsen, Stephen D. McCormick, Craig R. Primmer, Anna Wargelius
Evolutionary Applications p. 1-16
2020

Indel locations are determined by template polarity in highly efficient in vivo CRISPR/Cas9- mediated HDR in Atlantic salmon

Anne Hege Straume, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Hilal Guralp, Lene Kleppe, Anna Wargelius, Rolf Brudvik Edvardsen
Scientific Reports 10
2019

The influence of vgll3 genotypes on sea age at maturity is altered in farmed mowi strain Atlantic salmon

Fernando Ayllon, Monica Favnebøe Solberg, Kevin Glover, Faezeh Mohammadi, Erik Nordtorp Kjærner-Semb, Per Gunnar Fjelldal, Eva Andersson, Tom Johnny Hansen, Rolf Edvardsen, Anna Wargelius
BMC Genetics 20:44 p. 1-8
2018

Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis

Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Lene Kleppe, Elin Sørhus, Kai Ove Skaftnesmo, Tomasz Furmanek, Frida Thyri Segafredo, Anders Thorsen, Per Gunnar Fjelldal, Tom Johnny Hansen, Geir Lasse Taranger, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius, Rolf Edvardsen
Scientific Reports 8:1912 p. 1-11
2016

Atlantic salmon populations reveal adaptive divergence of immune related genes - A duplicated genome under selection

Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Vidar Wennevik, Geir Dahle, Eero Niemelä, Mikhail Ozerov, Juha-Pekka Vähä, Kevin Glover, Carl J. Rubin, Anna Wargelius, Rolf Edvardsen
BMC Genomics 17:610 p. 1-12
2015

The vgll3 Locus Controls Age at Maturity in Wild and Domesticated Atlantic Salmon(Salmo salar L.) Males

Fernando Ayllon, Erik Nordtorp Kjærner-Semb, Tomasz Furmanek, Vidar Wennevik, Monica Favnebøe Solberg, Geir Dahle, Geir Lasse Taranger, Kevin Glover, Markus Sällman Almén, Carl J. Rubin, Rolf Edvardsen, Anna Wargelius
PLoS Genetics 11:e1005628

Annet tidsskriftbidrag

2021

Author Correction: Rescue of germ cells in dnd crispant embryos opens the possibility to produce inherited sterility in Atlantic salmon (Scientific Reports, (2020), 10, 1, (18042), 10.1038/s41598-020-74876-2)

Hilal Güralp, Kai Ove Skaftnesmo, Erik Nordtorp Kjærner-Semb, Anne Hege Straume, Lene Kleppe, Rüdiger W. Schulz, Rolf Brudvik Edvardsen, Anna Wargelius
Scientific Reports 11
2016

Ulik laks i sør og nord

Erik Nordtorp Kjærner-Semb, Anna Wargelius, Rolf Edvardsen
Dagens næringsliv

Faglige foredrag

2024

Knockout av vgll3 gir sein kjønnsmodning i hannlaks

Kjærner-Semb, Erik Nordtorp
2024

Uses of biotechnology to control reproduction in Atlantic salmon

Lene Kleppe, Anna Sofie Troedsson Wargelius, Diego Crespo, Erik Nordtorp Kjærner-Semb, Kai Ove Skaftnesmo, Eva Andersson, Per Gunnar Fjelldal, Tom Johnny Hansen, Rolf Brudvik Edvardsen, Anders Thorsen, Rüdiger W. Schulz, Anne Torsvik, Grethe Beate Thorsheim, Anne Hege Straume, Petra Vogelsang, Ivar Helge Matre, Ann-Kathrin Jakobsen Kroken, Lise Dyrhovden, Audun Østby Pedersen, Simon Flavell, Florian Sambraus, Arnor Gullanger, Tone Knappskog
2024

Moving sterile Crispr salmon from the tank to sea cages - regulatory barriers and social impacts

Anna Sofie Troedsson Wargelius, Erik Nordtorp Kjærner-Semb, Anne Hege Straume, Per Gunnar Fjelldal, Jonatan Nilsson, Hilal Guralp, Kai Ove Skaftnesmo, Dorothy Jane Dankel, Eva Andersson, Lene Kleppe, Rolf Brudvik Edvardsen
2024

LACK OF VGLL3A DELAYS ONSET OF MALE MATURATION IN ATLANTIC SALMON

Kjærner-Semb, Erik Nordtorp
2024

Lack of vgll3a Delays Onset of Male Maturation in Atlantic Salmon

Kjærner-Semb, Erik Nordtorp
2023

Compensatory mechanism of NKAα1a in nkaα1b1/b2 Crispants during smoltification in Atlantic Salmon (Salmo salar)

Ross Fisher Cairnduff, Tom Ole Nilsen, Anna Sofie Troedsson Wargelius, Elsa Denker, Stephen D. McCormick, Erik Nordtorp Kjærner-Semb
2023

Lack of vgll3a delays onset of sexual maturation in Atlantic salmon (Salmo salar) males

Kjærner-Semb, Erik Nordtorp
2022

Kan genetiske tilpasninger i ferskvannlaks, avsløre genetikk bak smoltifisering?

Ross Fisher Cairnduff, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Eva Andersson, Monica Favnebøe Solberg, Craig Primmer, Kevin Alan Glover, Anna Sofie Troedsson Wargelius
2022

Adaptation in landlocked Atlantic salmon links genetics in wild and farmed salmon to smoltification.

Ross Fisher Cairnduff, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Eva Andersson, Monica Favnebøe Solberg, Kevin Alan Glover, Anna Sofie Troedsson Wargelius
2022

VGLL3A ALLELES AFFECT THE BRAIN-PITUITARY-GONAD AXIS IN ATLANTIC SALMON (SALMO SALAR) VIA REGULATION OF FSHB

Kjærner-Semb, Erik Nordtorp
2021

Functional genomic analysis of landlocked Atlantic salmon (Salmo Salar) populations.

Ross Fisher Cairnduff, Erik Nordtorp Kjærner-Semb, Eva Andersson, C. R. Primmer, William Bernard Perry, Anna Sofie Troedsson Wargelius
2021

Development of gene editing technology and applications in Atlantic salmon

Kjærner-Semb, Erik Nordtorp
2020

Hva er de genetiske forskjellene mellom ferskvannslaks og anadrom laks?.

Erik Nordtorp Kjærner-Semb, Rolf Brudvik Edvardsen, Fernando Ayllon, Tomasz Furmanek, Carl Johan Rubin, Tom Ole Nilsen, Vidar Wennevik, Craig Primmer, Anna Sofie Troedsson Wargelius
2019

Genomic regions under selection in landlocked Atlantic salmon. International Conference on Integrative Salmonid Biology

Erik Nordtorp Kjærner-Semb, Rolf Brudvik Edvardsen, Fernando Ayllon, Tomasz Furmanek, Carl-Johan Rubin, Vidar Wennevik, Tom Ole Nilsen, Craig Primmer, Anna Sofie Troedsson Wargelius
2019

Highly efficient CRISPR/Cas9 knock-in in Atlantic salmon

Rolf Brudvik Edvardsen, Anne Hege Straume, Erik Nordtorp Kjærner-Semb, hilal guralp, Lene Kleppe, Kai Ove Skaftnesmo, Anna Wargelius
2019

Genomic regions under selection in landlocked Atlantic salmon

Erik Nordtorp Kjærner-Semb, Rolf Brudvik Edvardsen, Fernando Ayllon, Tomasz Furmanek, Carl Johan Rubin, Vidar Wennevik, Tom Ole Nilsen, Stephen McCormic, Craig Primmer, Anna Wargelius
2018

Hvordan fungerer laksens pubertetsgen?

Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Lene Kleppe, Elin Sørhus, Kai Ove Skaftnesmo, Tomasz Furmanek, Frida Thyri Segafredo, Anders Thorsen, Per Gunnar Fjelldal, Tom Johnny Hansen, Geir Lasse Taranger, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius, Rolf Edvardsen
2016

Genome resequencing of geographically distinct Atlantic Salmon (Salmo salar) populations reveals adaptive divergence

Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Vidar Wennevik, Geir Dahle, Eero Niemelä, Mikhail Ozerov, Juha-Pekka Vähä, Kevin Glover, Carl Johan Rubin, Anna Wargelius
2016

Adaptive plasticity in Atlantic salmon- genetic predisposition of time at maturity and environmental triggers

Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Tomasz Furmanek, Tom Johnny Hansen, Per Gunnar Fjelldal, Carl Johan Rubin, Lene Kleppe, Kai Ove Skaftnesmo, Elin Sørhus, Faezeh Mohammadi, Geir Dahle, Vidar Wennevik, Monica Favnebøe Solberg, Kevin Glover, Birgitta Norberg, Geir Lasse Taranger, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius
2015

The vgll3 locus controls time of maturation in salmon

Kjærner-Semb, Erik Nordtorp
2014

Mario: Interactive Tuning of Biological Analysis Pipelines Using Iterative Processing

Martin Ernstsen, Erik Nordtorp Kjærner-Semb, Nils Peder Willassen, Lars Ailo Bongo

Poster

2022

VGLL3A PÅVIRKER HJERNE-HYPOFYSE-GONADE AKSEN I ATLANTISK LAKS (SALMO SALAR) VIA REGULERING AV FSHB

Kjærner-Semb, Erik Nordtorp
2022

VGLL3A CONNECTS TO THE ATLANTIC SALMON (SALMO SALAR) BRAIN-PITUITARY-GONAD AXIS THROUGH REGULATION OF FSHB

Kjærner-Semb, Erik Nordtorp
2021

Long-term performance of gene edited, sterile Atlantic salmon - growth, smoltification, welfare indicators and fillet composition.

Lene Kleppe, Per Gunnar Fjelldal, Eva Andersson, Tom Johnny Hansen, Monica Sanden, Aina Bruvik, Kai Ove Skaftnesmo, Tomasz Furmanek, Erik Nordtorp Kjærner-Semb, Diego Crespo, Simon Flavell, Audun Ø. Pedersen, Petra Vogelsang, Anne Torsvik, Sara Olausson, Birgitta Norberg, Rüdiger W. Schulz, Jan Bogerd, Nina Santi, Rolf Brudvik Edvardsen, Anna Wargelius
2021

VGLL3A ALLELES AFFECT THE BRAIN-PITUITARY-GONAD AXIS IN ATLANTIC SALMON (SALMO SALAR) VIA REGULATION OF FSHB

Kjærner-Semb, Erik Nordtorp
2019

Exploring beneficial genetic variants in Atlantic salmon using gene editing

Erik Nordtorp Kjærner-Semb, Anna Wargelius, Rolf Brudvik Edvardsen
2018

VGLL3 AND THE HIPPO PATHWAY ARE REGULATED IN SERTOLI CELLS UPON ENTRY AND DURING PUBERTY IN ATLANTIC SALMON TESTIS.

Erik Nordtorp Kjærner-Semb, Fernando Ayllon, Lene Kleppe, Elin Sørhus, Kai Ove Skaftnesmo, Tomasz Furmanek, Frida Thyri Segafredo, Anders Thorsen, Per Gunnar Fjelldal, Tom Johnny Hansen, Geir Lasse Taranger, Eva Andersson, Rüdiger W. Schulz, Anna Wargelius, Rolf Edvardsen
2016

Genome resequencing shows adaptive divergence in Atlantic salmon

Kjærner-Semb, Erik Nordtorp
2015

The vgll3 locus controls time of maturity in salmon

Kjærner-Semb, Erik Nordtorp

Rapporter og avhandlinger

2022

FUNCTIONAL CHARACTERIZA TION OF GPR132 AND CADM1 AND THEIR POTENTIAL ROLES IN DISEASE RESISTANCE IN ATLANTIC SALMON (SALMO SALAR)

Marte Bårvåg Nesse, Anna Sofie Troedsson Wargelius, Erik Nordtorp Kjærner-Semb
2017

Genetics behind puberty and adaptation in Atlantic Salmon revealed by genomic studies

Anna Wargelius, Rolf Edvardsen, Erik Nordtorp Kjærner-Semb, Kevin Glover
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